Get PDF Lung Cancer Metastasis: Novel Biological Mechanisms and Impact on Clinical Practice

Free download. Book file PDF easily for everyone and every device. You can download and read online Lung Cancer Metastasis: Novel Biological Mechanisms and Impact on Clinical Practice file PDF Book only if you are registered here. And also you can download or read online all Book PDF file that related with Lung Cancer Metastasis: Novel Biological Mechanisms and Impact on Clinical Practice book. Happy reading Lung Cancer Metastasis: Novel Biological Mechanisms and Impact on Clinical Practice Bookeveryone. Download file Free Book PDF Lung Cancer Metastasis: Novel Biological Mechanisms and Impact on Clinical Practice at Complete PDF Library. This Book have some digital formats such us :paperbook, ebook, kindle, epub, fb2 and another formats. Here is The CompletePDF Book Library. It's free to register here to get Book file PDF Lung Cancer Metastasis: Novel Biological Mechanisms and Impact on Clinical Practice Pocket Guide.

The E-mail Address es field is required. Please enter recipient e-mail address es. The E-mail Address es you entered is are not in a valid format. Please re-enter recipient e-mail address es.

ADVERTISEMENT

You may send this item to up to five recipients. The name field is required. Please enter your name. The E-mail message field is required. Please enter the message. Please verify that you are not a robot. Would you also like to submit a review for this item? You already recently rated this item. Your rating has been recorded.

Kundrecensioner

Write a review Rate this item: 1 2 3 4 5. Preview this item Preview this item. Subjects Medicine. Biomedicine View all subjects More like this Similar Items. Find a copy online Links to this item doi. Allow this favorite library to be seen by others Keep this favorite library private. Find a copy in the library Finding libraries that hold this item Reviews User-contributed reviews Add a review and share your thoughts with other readers.

Be the first. Add a review and share your thoughts with other readers. Similar Items Related Subjects: 7 Medicine. Biomedicine Cancer -- Research. Cancer -- Research Medicine Oncology. Metastases to the carpal bones are much rarer than those to the metacarpal and phalangeal bones.

Lung Cancer Metastasis: Novel Biological Mechanisms and Impact on Clinical Practice / Edition 1

For this reason, a metastasis in the carpus is more often misdiagnosed. The described case regards a metastasis from severely undifferentiated large-cell lung carcinoma. Large cell carcinoma is classified among the non-small-cell lung carcinomas NSCLCs , which comprise a heterogeneous group of histology types, with the most frequent types being adenocarcinoma, squamous cell carcinoma, large cell carcinoma, adenosquamous carcinoma and sarcomatoid carcinoma.

The first physician based his diagnosis on clinical symptoms pain at motion of the left thumb, not at rest , probably waiting upon the results of his therapy. The combination of the clinical and radiological pictures could actually induce the suspicion of thumb osteoarthritis. The radiological picture of diffuse osteoporosis led the physician to think of a diffused disuse osteoporosis, caused by the severe pain.

When the patient presented to the third physician it was an emergency admission to an internal medicine department because progressive worsening of his general condition was evident as well as an enormous swelling of the left hand. The correct diagnosis would have been made sooner if the patient had presented at the requested follow-ups. An early diagnosis was not easy, but the first two physicians examining the patient might have been too superficial in their anamnesis, clinical examinations and X-ray interpretations. One more clue should have been the fact that the patient was a heavy cigarette smoker.

Novel Biological Mechanisms and Impact on Clinical Practice

These facts should have made the two physicians suspicious. Moreover, the second physician underestimated the radiological signs of diffuse osteoporosis which were probably, in part, areas of osteolysis. It was probably not logical to imagine a malignant location on the basis of the data that arose from the first clinical examinations and X-rays.

The rarity of metastases to the distal regions of the limbs can induce a physician to suspect a primary tumor of the hand. They are rare, too, especially in the carpal bones.

TRACO 2018 - Non-small cell lung cancer and Genomics

When a metastasis to the hand is discovered, it is very probable that other previous metastases are disseminated in the skeleton, because metastases of hand bones generally indicate very advanced primary tumors. The hand as the first location of metastasis is the main peculiarity of the presented case. Metastases to the hand are rare, but those to the carpal bones are even rarer. The location of the lesion at the trapezium, as the first X-rays showed, led the examining physicians to suspect other disorders. The described case was not easy to diagnose because of the poor compliance of the patient and the rarity of carpal bone metastasis.

Written informed consent was obtained from the patient for the publication of this case report and its accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal. GR operated on the patient and was a major contributor in writing the manuscript. AC interpreted the patient's histological data. RA collected all the data in the anamnesis of the patient, and contacted the colleagues from Oncology, Pathology and Chest Surgery, to receive a multidisciplinary opinion about the case.

All authors read and approved the final manuscript. National Center for Biotechnology Information , U. J Med Case Rep.

Published online Nov Author information Article notes Copyright and License information Disclaimer. Corresponding author. Giuseppe Rinonapoli: ti. Received Nov 1; Accepted Oct 3.


  • Lung Cancer Metastasis?
  • Japans Peace-Building Diplomacy in Asia: Seeking a More Active Political Role (Routledge Security in Asia Pacific Series).
  • A Tangle of Tales: short stories for children.
  • Best! - No Need to Be Cheap If You Are....

This article has been cited by other articles in PMC. Abstract Introduction A first metastasis to the hand is extremely rare. Case presentation A year-old Caucasian man was submitted to several physical examinations for thumb pain. Conclusion Less than 20 case reports are available in the literature dealing with metastases to carpal bones. Case presentation A year-old Caucasian man, who was a regular drinker and heavy cigarette smoker, presented to a rheumatologist for pain at motion of his left thumb.

Open in a separate window. Figure 1. Figure 2. Figure 3.

watch

Lung Cancer Metastasis: Novel Biological Mechanisms and Impact on Clinical - Google книги

Figure 4. Chest computed tomography scan revealing a mass in the superior left lobe arrow.


  • Cloud-Service-Management: HMD - Praxis der Wirtschaftsinformatik 288 (German Edition).
  • Exploring the microRNA profiles as potential diagnostic prob : Medicine.
  • Crimson Fire (Dreamers Cycle Series).
  • Shop Lung Cancer Metastasis Novel Biological Mechanisms And Impact On Clinical Practice;

Figure 5. Figure 6. Figure 7. Figure 8. Conclusion The described case was not easy to diagnose because of the poor compliance of the patient and the rarity of carpal bone metastasis. Consent Written informed consent was obtained from the patient for the publication of this case report and its accompanying images.

Competing interests The authors declare that they have no competing interests. Authors' contributions GR operated on the patient and was a major contributor in writing the manuscript. Incidence, location and diagnostic evaluation of metastatic bone disease.

Read Lung Cancer Metastasis: Novel Biological Mechanisms and Impact on Clinical Practice Ebook

Orthop Clin North Am. Cancer Statistics. CA Cancer J Clin. The clinical course of bone metastases from breast cancer. Br J Cancer. Upper limb bone metastases. Tech Orthop. New York: Churchill Livingstone; Bone metastases; pp.